梅林，教授、博導，天津市生物醫學材料重點實驗室主任。2003年獲復旦大學藥學學士，2007年獲北京協和醫學院生物醫學工程博士。作為第一完成人，獲天津市自然科學獎二等獎、深圳市自然科學獎二等獎、中華醫學科技獎、深圳市青年科技獎。2021年起入選全球高被引科學家、國家健康科普專家，獲國家優秀青年科學基金等資助。 院校引進人才，2022年加入院校，此前任中山大學“百人計劃”教授、清華大學深圳國際研究生院副教授、清華博士后、新加坡國立大學博士后。

長期從事藥物載體材料和先進遞釋系統研究；承擔國家重點研發計劃課題等20余項國家和省部級科研課題，在Science Translational Medicine等雜志發表論文100余篇，H指數70，4次入選高被引科學家。主編專著1部，參編3部。培養博士、碩士、博士后30余名。擔任Smart Materials in Medicine和VIEW副主編，Journal of Controlled Release、Asian Journal of Pharmaceutical Sciences和Chinese Chemical Letters編委。

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1．Lu S, Shi Z, Ding C, Wang W, Zhang W, Huang L, Lin J, Wang X, Luo R, Zeng X, Zhou W, Chen H*, Wang Q*, Mei L*. BRD4-targeted photodegradation nanoplatform for light activatable melanoma therapy. Biomaterials. 2025, 317:123101.

2．Yunfei Yi, Zhangwen Peng, Yuanqi Liu, Huisong Hao, Liu Yu, Simin Wen, Shengjie Sun, Jianlin Shi*, Meiying Wu*, Lin Mei*. siRNA micelleplexes-mediated glutamine metabolism re-engineering for vascular normalization-boosted photo-immunotherapy. Acta Pharm Sin B. 2025, 15(4):2237-2252.

3．Sheng S, Zhang Y, Jin L, Sun W, Zhu D, Mei L*, Dong X*, Lv F*. A ferritin-targeted biohybrid triggering ferroptosis immunotherapy via activating endogenous iron and replenishing exogenous iron simultaneously. Nat Commun. 2025 Jul 1;16(1):6045.

4．Zhang H, Zhang Y, Zhang Y, Li H, Ou M, Yu Y, Zhang F, Yin H, Mao Z*, Mei L*. Catalytic activity of violet phosphorus-based nanosystems and the role of metabolites in tumor therapy. Nat Commun. 2024, 15(1):6783.

5．Yu Y, Li T, Ou M, Luo R, Chen H, Ren H, Li Z, Sun J, Zhang H, Peng S, Zhao Y, Mei L*.  OX40L-expressing M1-like macrophage exosomes for cancer immunotherapy. J Control Release. 2024;365:469-479. （ESI）

6．Yu Y, Zhang F, Xiao W, Cheng Q, Li T, Tang J, Tao W, Mei L*. Adaptive Design of Nanovesicles Overcoming Immunotherapeutic Limitations of Chemotherapeutic Drugs through Poliovirus Receptor Blockade. ACS Nano 2024, 18(7): 5915–5929.

7．Shi Z, Luo M, Huang Q, Ding C, Wang W, Wu Y, Luo J, Lin C, Chen T, Zeng X, Mei L*, Zhao Y*, Chen H*. NIR-dye bridged human serum albumin reassemblies for effective photothermal therapy of tumor. Nat Commun. 2023;14(1):6567.

8．Yongkang Yu#, Qinzhen Cheng#, Xiaoyuan Ji, Hongzhong Chen, Wenfeng Zeng, Xiaowei Zeng*, Yanli Zhao*, Lin Mei*. Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of postsurgical cancer recurrence and metastasis. Science Advances, 2022, 8(49): eadd3599. (ESI, C100)

9．Zeng W, Yu M, Chen T, Liu Y, Yi Y, Huang C, Tang J, Li H, Ou M, Wang T, Wu M*, Mei L*. Polypyrrole Nanoenzymes as Tumor Microenvironment Modulators to Reprogram Macrophage and Potentiate Immunotherapy. Adv Sci. 2022, 9(23):2201703. （ESI, C100）

10．Chen T, Zeng WW, Tie CJ, Yu M, Hao HS, Deng Y, Li QQ, Zheng HR*, Wu MY*, Mei L*. Engineered gold/black phosphorus nanoplatforms with remodeling tumor microenvironment for sonoactivated catalytic tumor theranostics. Bioactive Materials 2022;10:515-525. （ESI, C100）

11．Lin YX#, Wang Y#, Ding JX, Jiang AP, Wang J, Yu M, Blake S, Liu SS, Bieberich CJ, Farokhzad OC*, Mei L*, Wang H*, Shi JJ*. Tumor suppressor reactivation by mRNA nanoparticles induces anti-tumor immunity and improves immune checkpoint blockade therapy. Science Translational Medicine 2021;599(13):eaba9772.（ESI, F100, C100）

12．Zhang F, Lu G, Wen X, Li F, Ji X, Li Q, Wu M, Cheng Q, Yu Y, Tang J, Mei L*. Magnetic nanoparticles coated with polyphenols for spatio-temporally controlled cancer photothermal/ immunotherapy. J Control Release. 2020;326:131-139. （ESI, C100）

13．Ye Xinyu, Liang Xin, Chen Qian, Miao Qianwei, Chen Xiuli, Zhang Xudong*, Mei Lin*. Surgical Tumor-Derived Personalized Photothermal Vaccine Formulation for Cancer Immunotherapy. ACS Nano 2019;13(3);2956-2968. （ESI, C100）

14．Zeng X#, Luo M#, Liu G#, Wang XS, Tao W, Lin Y, Ji XY, Nie L, Mei L*. Polydopamine-modified black phosphorous nanocapsule with enhanced stability and photothermal performance for tumor multimodal treatments. Advanced Science 2018, 5(10): 1800510. （ESI, C100）

15．Tao W#, Zhu X#, Yu X#, Zeng X, Xiao Q, Zhang X, Ji X, Wang X, Shi J*, Zhang H*, Mei L*. Black phosphorus nanosheets as a robust delivery platform for cancer theranostics. Advanced Materials., 2017; 29 (1): 1603276.（ESI, C100）