戴均貴，1969年生，籍貫湖北浠水，藥物研究所研究員，博士生導(dǎo)師，研究方向為天然藥物合成生物學(xué)。1987年考入華中師范大學(xué)生物學(xué)專業(yè)，1991年獲學(xué)士學(xué)位；1993年在華中師范大學(xué)植物學(xué)專業(yè)攻讀碩士學(xué)位；1996年在中國協(xié)和醫(yī)科大學(xué)生藥學(xué)專業(yè)攻讀博士學(xué)位，從事天然藥物生物合成研究。1999、2001年分別進入北京大學(xué)藥學(xué)院、日本新瀉大學(xué)化學(xué)系（JSPS）進行博士后研究工作，主要從事天然藥物生物合成與生物催化研究。2004年為副研究員，2007年晉升為研究員。

針對天然藥物面臨的資源匱乏、成藥性不足等關(guān)鍵科學(xué)問題，開展重要珍稀藥用天然產(chǎn)物的生物合成與分子創(chuàng)新研究，揭示天然藥物生物合成規(guī)律并重構(gòu)生物合成途徑，并實現(xiàn)可設(shè)計性、高效分子創(chuàng)新。

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1. Yangyang Duan#, Wenyu Du#, Zhijun Song, Ridao Chen, Kebo Xie, Jimei Liu, Dawei Chen*, Jungui Dai*. Functional characterization of a cycloartenol synthase and four glycosyltransferases in the biosynthesis of cycloastragenol-type astragalosides from Astragalus membranaceus. Acta Pharmaceutica Sinica B, https://doi.org/10.1016/j.apsb.2022.05.015. (IF=14.903)

2. Lei Gao#, Cong Su#, Xiaoxia Du#, Ruishan Wang#, Shuming Chen, Yu Zhou, Chengwei Liu, Xiaojing Liu, Runze Tian, Liyun Zhang, Kebo Xie, She Chen, Qianqian Guo, Lanping Guo, Yoshio Hano, Manabu Shimazaki, Atsushi Minami, Hideaki Oikawa, Niu Huang, K. N. Houk, Luqi Huang*, Jungui Dai*, Xiaoguang Lei*. FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nature Chemistry, 2020, 12 (7): 620–628. (IF=24.427, F1000)

3. Kebo Xie#*, Xiaolin Zhang#, Songyang Sui, Fei Ye*, and Jungui Dai*. Exploring and applying the substrate promiscuity of a C-glycosyltransferase in the chemo-enzymatic synthesis of bioactive C-glycosides. Nature Communications, 2020, 11 (1), 5162. (IF=14.919)

4. Dawei Chen, Shuai Fan, Ridao Chen, Kebo Xie, Sen Yin, Lili Sun, Jimei Liu, Lin Yang, Jianqiang Kong, Zhaoyong Yang, and Jungui Dai*. Probing and engineering key residues for bis-C-glycosylation and promiscuity of a C-glycosyltransferase. ACS Catalysis, 2018, 8 (6), 4917-4927. (IF=12.221)

5. Dawei Chen, Ridao Chen, Kebo Xie, Tian Yue, Xiaolin Zhang, Fei Ye, and Jungui Dai*. Biocatalytic C-glucosylation of coumarins using an engineered C-glycosyltransferase. Organic Letters, 2018, 20 (6), 1634-1637. (IF=6.555)

6. Ridao Chen#, Bingquan Gao#, Xiao Liu#, Feiying Ruan, Yong Zhang, Jizhong Lou, Keping Feng, Carsten Wunsch, Shu-Ming Li, Jungui Dai*, Fei Sun*. Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase. Nature Chemical Biology, 2017, 13 (2), 226-234. (IF=13.843, F1000)

7. Kebo Xie, Ridao Chen, Dawei Chen, Jianhua Li, Ruishan Wang, Lin Yang and Jungui Dai*. Enzymatic N-glycosylation of diverse arylamine aglycons by a promiscuous glycosyltransferase from Carthamus tinctorius. Advanced Synthesis & Catalysis, 2017, 359 (4), 603-608. (IF=5.123)

8. Dawei Chen, Ridao Chen, Ruishan Wang, Jianhua Li, Kebo Xie, Chuancai Bian, Lili Sun, Xiaolin Zhang, Jimei Liu, Lin Yang, Fei Ye, Xiaoming Yu, and Jungui Dai*. Probing the catalytic promiscuity of a regio- and stereo-specific C-glycosyltransferase from Mangifera indica. Angewandte Chemie International Edition, 2015, 54 (43), 12678-12682. (IF=11.709)

9. Dewu Zhang, Xiaoyu Tao, Ridao Chen, Jimei Liu, Li Li, Xiaomei Fang, Liyan Yu, and Jungui Dai*. Pericoannosin A, a polyketide synthase–nonribosomal peptide synthetase hybrid metabolite with new carbon skeleton from the endophytic fungus Periconia sp. Organic Letters, 2015, 17 (17), 4304-4307. (IF=6.732)

10. Ridao Chen, Xiao Liu, Jianhua Zou, Yunze Yin, Bin Ou, Jianhua Li, Ruishan Wang, Dan Xie, Peicheng Zhang, Jungui Dai*. Regio- and stereospecific prenylation of flavonoids by Sophora flavescens prenyltransferase. Advanced Synthesis & Catalysis, 2013, 355 (9), 1817–1828. (IF=5.542)