劉龍丁，1969年生，籍貫內(nèi)蒙古呼和浩特，醫(yī)學生物學研究所研究員，博士生導師，研究方向病毒疫苗學。1987年考入云南大學微生物學專業(yè)，1991年獲得學士學位。1999年在中國協(xié)和醫(yī)科大學免疫學專業(yè)攻讀碩士學位，從事病毒與宿主相互作用研究。2005年在北京協(xié)和醫(yī)學院免疫學專業(yè)攻讀博士學位，從事病毒免疫學研究。2008年受聘為中國醫(yī)學科學院研究員，從事腸道病毒和呼吸道病毒疫苗研發(fā)評價。

呼吸道病毒感染致病機制研究及疫苗研發(fā)；腸道病毒感染機制研究及疫苗研發(fā)；以單克隆抗體為導向的新型疫苗設(shè)計和評價；以單細胞測序技術(shù)為基礎(chǔ)的新型疫苗評價體系的探究。

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1. Zheng H#, Chen Y#, Li J#, Li H#, Zhao X#, Li J#, Yang F, Li Y, Liu C, Qin L, Zuo Y, Zhang Q, He Z*, Shi H*, Li Q*, Liu L*. Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques. Cell Rep. 2022 May 24;39(8):110864. (IF=9.995)

2. Li H#, Zhao X#, Zhao Y#, Li J#, Zheng H#, Xue M, Guo L, Zhou J, Yang J, Zuo Y, Chen Y, Yang Z, Fan Q, Qin L, Shi H, Liu L*. H1N1 exposure during the convalescent stage of SARS-CoV-2 infection results in enhanced lung pathologic damage in hACE2 transgenic mice. Emerg Microbes Infect. 2021 Dec;10(1):1156-1168. (IF=19.568)

3. Guo L, Li N, Yang Z, Li H, Zheng H, Yang J, Chen Y, Zhao X, Mei J, Shi H, Worthen GS, Liu L. Role of CXCL5 in Regulating Chemotaxis of Innate and Adaptive Leukocytes in Infected Lungs Upon Pulmonary Influenza Infection. Front Immunol. 2021 Nov 18;12:785457. (IF=8.786)

4. Zheng H#, Li H#, Guo L#, Liang Y#, Li J#, Wang X, Hu Y, Wang L, Liao Y, Yang F, Li Y, Fan S, Li D, Cui P, Wang Q, Shi H, Chen Y, Yang Z, Yang J, Shen D, Cun W, Zhou X, Dong X, Wang Y, Chen Y, Dai Q, Jin W, He Z*, Li Q*, Liu L*. Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression. PLoS Pathog. 2020 Nov 12;16(11):e1008949. (IF=6.823)

5. Guo L#, Li N#, Li W, Zhou J, Ning R, Hou M*, Liu L*. New hemagglutinin dual-receptor-binding pattern of a human-infecting influenza A (H7N9) virus isolated after fifth epidemic wave. Virus Evol. 2020 Apr 20;6(1):veaa021. (IF=7.989)

6. Zheng H#, Wang J#, Li B#, Guo L, Li H, Song J, Yang Z, Li H, Fan H, Huang X, Long H, Cheng C, Chu M, He Z, Yu W, Li J, Gao Y, Ning R, Li N, Yang J, Wu Q, Shi H, Sun M*, Liu L*. A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice. J Immunol. 2018 Nov 1;201(9):2557-2569. (IF=4.718)

7. Guo L#, Feng K#, Wang YC#, Mei JJ, Ning RT, Zheng HW, Wang JJ, Worthen GS, Wang X, Song J, Li QH, Liu LD*. Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection. Mucosal Immunol. 2017 Nov;10(6):1529-1541. (IF=7.36)

8. Liu L#, Mo Z#, Liang Z#, Zhang Y, Li R, Ong KC, Wong KT, Yang E, Che Y, Wang J, Dong C, Feng M, Pu J, Wang L, Liao Y, Jiang L, Tan SH, David P, Huang T, Zhou Z, Wang X, Xia J, Guo L, Wang L, Xie Z, Cui W, Mao Q, Liang Y, Zhao H, Na R, Cui P, Shi H, Wang J*, Li Q*. Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations. BMC Med. 2015 Sep 17;13:226. (IF=8.005)

9. Li R#, Liu L#, Mo Z#, Wang X#, Xia J#, Liang Z#, Zhang Y, Li Y, Mao Q, Wang J, Jiang L, Dong C, Che Y, Huang T, Jiang Z, Xie Z, Wang L, Liao Y, Liang Y, Nong Y, Liu J, Zhao H, Na R, Guo L, Pu J, Yang E, Sun L, Cui P, Shi H, Wang J*, Li Q*. An inactivated enterovirus 71 vaccine in healthy children. N Engl J Med. 2014 Feb 27;370(9):829-37. (IF=53.125, ESI)

10. Liu L#, Zhang Y#, Wang J, Zhao H, Jiang L, Che Y, Shi H, Li R, Mo Z, Huang T, Liang Z, Mao Q, Wang L, Dong C, Liao Y, Guo L, Yang E, Pu J, Yue L, Zhou Z, Li Q*. Study of the integrated immune response induced by an inactivated EV71 vaccine. PLoS One. 2013;8(1):e54451. (IF=4.078, F1000）