程濤，中國(guó)工程院院士，中國(guó)醫(yī)學(xué)科學(xué)院學(xué)術(shù)咨詢委員會(huì)學(xué)部委員，博士研究生導(dǎo)師，北京協(xié)和醫(yī)學(xué)院干細(xì)胞與再生醫(yī)學(xué)系主任，中國(guó)醫(yī)學(xué)科學(xué)院血液病醫(yī)院（中國(guó)醫(yī)學(xué)科學(xué)院血液學(xué)研究所）所院長(zhǎng)，血液與健康全國(guó)重點(diǎn)實(shí)驗(yàn)室主任。主持國(guó)家重大科研項(xiàng)目和人才（創(chuàng)群、杰青等）項(xiàng)目17項(xiàng)，以第一完成人獲國(guó)家自然科學(xué)二等獎(jiǎng)、全國(guó)創(chuàng)新爭(zhēng)先獎(jiǎng)、吳楊獎(jiǎng)、天津市自然科學(xué)特等獎(jiǎng)等獎(jiǎng)項(xiàng)，入選科睿唯安“全球高被引科學(xué)家”及“全球前2%頂尖科學(xué)家”。

長(zhǎng)期從事造血干細(xì)胞基礎(chǔ)與轉(zhuǎn)化研究，針對(duì)放化療、骨髓移植或嚴(yán)重核輻射損傷所致造血障礙難題，聚焦血液系統(tǒng)的“種子”——造血干細(xì)胞（HSC），取得系列突破性成果：創(chuàng)立“干細(xì)胞效能”學(xué)說，發(fā)現(xiàn)具有超級(jí)移植潛力的高效能HSC，并揭示其失能的關(guān)鍵機(jī)制；提出“血液生態(tài)”概念，解碼血液生態(tài)形成與重建，制定抗氧化造血重建新策略并獲得臨床驗(yàn)證；建立修復(fù)凍存臍血造血活性新方法，開發(fā)新型造血細(xì)胞系列產(chǎn)品，拓展更多臨床應(yīng)用場(chǎng)景。

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1. Dong F#, Zhang S#, Zhu C#, Yang Z#, Wang L, Ma Y, Lu J, Li X, Wang X, Wang N, Zhang S, Xie M, Wang J, Zhang X, Zheng Y, Ma S, Ema H, Cheng H, Hao S, Suda T, Lan Y, Liu B, Zhu P*, Junren Chen J*, Cheng T*. Heterogeneity of high-potency multi-lineage hematopoietic stem cells and identification of ‘Super’ transplantability. Blood. 2025 Jul 31;146(5):546-557. (IF=23.1)

2. Huang Y#, Xie X#, Liu M#, Zhang Y#, Yang J, Yang W, Hu Y, Qi S, Feng Y, Liu G, Lu S, Peng X, Ye J, Ma S, Sun J, Wang L, Hu L, Wang L, Zhu X, Cheng H, Sun Z, Chen J, Dong F*, Zhang Y*, Cheng T*. Restoring mitochondrial function promotes hematopoietic reconstitution from cord blood following cryopreservation-related functional decline. J Clin Invest. 2025 Mar 4:e183607. (IF=13.3)

3. Lv H#, Wang C#, Liu Z#, Quan M, Li K, Gou F, Shi X, Liu Q, Yv Y, Zhu P, Cheng H*, Cheng T*, Ai D*. Suppression of the Prostaglandin I2-Type 1 Interferon Axis Induces Extramedullary Hematopoiesis to Promote Cardiac Repair After Myocardial Infarction. Circulation. 2025 Apr 28; 151(24):1730-1747. (IF=38.7)

4. Li JJ#, Liu J#, Li YE, Chen LV, Cheng H*, Li Y*, Cheng T*, Wang QF*, Zhou B*. Differentiation route determines the functional outputs of adult megakaryopoiesis. Immunity. 2024 Mar 12;57(3):478-494.e6. (IF=26.3)

5. Shen J#, Lyu S#, Xu Y#, Zhang S, Li L, Li J, Mou J, Xie L, Tang K, Wen W, Peng X, Yang Y, Shi Y, Li X, Wang M, Li X*, Wang J*, Cheng T*. Activating innate immune responses repolarizes hPSC-derived CAR macrophages to improve anti-tumor activity. Cell Stem Cell. 2024 Jul 5;31(7):1003-1019.e9. (IF=20.4)

6. Zheng Z#, Yang S#, Gou F#, Tang C#, Zhang Z#, Gu Q, Sun G, Jiang P, Wang N, Zhao X, Kang J, Wang Y, He Y, Yang M, Lu T, Lu S, Qian P*, Zhu P*, Cheng H*, Cheng T*. The ATF4-RPS19BP1 axis modulates ribosome biogenesis to promote erythropoiesis. Blood. 2024 Aug 15;144(7):742-756. (IF=23.1, F1000)

7. Huo Y#, Wu L#, Pang A#, Li Q#, Hong F#, Zhu C, Yang Z, Dai W, Zheng Y, Meng Q, Sun J, Ma S, Hu L, Zhu P, Dong F, Gao X, Jiang E*, Hao S*, Cheng T*. Single-cell dissection of human hematopoietic reconstitution after allogeneic hematopoietic stem cell transplantation. Sci Immunol. 2023 Mar 17;8(81):eabn6429. (IF=17.8)

8. Wang H#, Liu C#, Xie X#, Niu M#, Wang Y#, Cheng X#, Zhang B#, Zhang D, Liu M, Sun R, Ma Y, Ma S, Wang H, Zhu G, Lu Y, Huang B, Su P, Chen X, Zhao J, Wang H, Shen L, Fu L, Huang Q, Yang Y, Wang H, Wu C, Ge W, Chen C, Huo Q, Wang Q, Wang Y, Geng L, Xie Y, Xie Y, Liu L, Qi J, Chen H, Wu J, Jiang E, Jiang W, Wang X*, Shen Z*, Guo T*, Zhou J*, Zhu P*, Cheng T*. Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection. Immunity. 2023 Jun 13;56(6):1410-1428.e8. (IF=25.5)

9. Zhang YC#, Wang SC#, Zhang JL#, Liu C#, Li XQ#, Guo WB, Duan YJ, Zong SY, Zheng JR, Wu YX, Chen XL, Chen XY, Cheng XL, Chang YX, Wang Y, Ding F, Yang WY, Chen XJ, Guo Y, Zhang L, Chen YM, Zou Y, Zhu XF*, Gu J*, Cheng T*. Elucidating minimal residual disease of pediatric B cell acute lymphoblastic leukemia by single cell analysis. Nat Cell Biol. 2022 Feb;24(2):242-252. (IF=21.3)

10. Dong F#, Hao S#, Zhang S#, Zhu C#, Cheng H#, Yang Z, Hamey FK, Wang X, Gao A, Wang F, Gao Y, Dong J, Wang C, Wang J, Lan Y, Liu B, Ema H, Tang F, G?ttgens B*, Zhu P*, Cheng T*. Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis. Nat Cell Biol. 2020 Jun;22(6):630-639. (IF=28.8, F1000)