張金蘭，1969年生，籍貫內(nèi)蒙古呼和浩特，藥物分析學(xué)家，藥物研究所研究員，博士生導(dǎo)師。1987年考入北京醫(yī)科大學(xué)藥學(xué)專業(yè)，1992年獲得學(xué)士學(xué)位。1992年在中國協(xié)和醫(yī)科大學(xué)藥物分析專業(yè)攻讀碩士學(xué)位，從事中藥成分分離和分析研究。1999年在中國協(xié)和醫(yī)科大學(xué)藥物分析專業(yè)攻讀博士學(xué)位，從事中草藥代謝產(chǎn)物分析研究。2002年進(jìn)入北京大學(xué)醫(yī)學(xué)部進(jìn)行博士后研究工作，主要研究中草藥成分分析和體內(nèi)代謝研究。 1998年升為助理研究員。2000年破格升為副研究員，2007年聘任為研究員。

聚焦藥物分析新技術(shù)及方法研究與應(yīng)用。構(gòu)建基于色譜質(zhì)譜聯(lián)用和多維數(shù)據(jù)分析的藥物分析關(guān)鍵技術(shù)平臺，重點(diǎn)解決藥物關(guān)鍵質(zhì)量屬性和體內(nèi)分析技術(shù)瓶頸，支撐藥物質(zhì)量分析、藥代動力學(xué)研究和藥效評價。

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1. Jin-Lan Zhang#, Yu-Huan Li#, Lu-Lu Wang#, Hong-Qi Liu#, Shuai-Yao Lu#, Yong Liu, Ke Li, Bin Liu, Su-Yun Li, Feng-Min Shao, Kun Wang, Ning Sheng, Rui Li, Jin-Jin Cui, Pei-Chun Sun, Chun-Xia Ma, Bo Zhu, Zhe Wang, Yuan-Hao Wan, Shi-Shan Yu, Yongsheng Che, Chao-Yang Wang, Chen Wang, Qiangqian Zhang, Li-Min Zhao, Xiao-Zhong Peng*, Zhenshun Cheng*, Jun-Biao Chang* , Jian-Dong Jiang*, Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients,  Signal Transduction & Targeted Therapy, 2021, 6(1), 414. (IF=38.104)

2. Zhe Wang#, Fan Zhang#, Wei Liu, Ning Sheng, Hua Sun*, Jinlan Zhang*. Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide. Journal of Pharmaceutical Analysis,  2021, 11, 764-775. (IF=14.026)

3. Miao Lin#, Menglin Li#, Hao Zheng, Haidan Sun, Jinlan Zhang*. Lipoprotein proteome profile: novel insight into hyperlipidemia, Clinical and Translational Medicine.2021, doi=10.1002/ctm2.361.(IF=8.554)

4. Menglin Li#, Hao Zheng, Miao Lin, Wenwen Zhu, Jinlan Zhang*. Characterization of the protein and peptide of excipient zein by the multienzyme digestion coupled with nano-LC-MS/MS. Food Chemistry, 2020, 321: 126712. (IF=7.514)

5. Wenwen Zhu#, Menglin Li#, Jinlan Zhang*, Integrating Intact Mass Analysis and Middle-Down Mass Spectrometry Approaches to Effectively Characterize Trastuzumab and Adalimumab Structural Heterogeneity.  Journal of Proteome Research, 2020. doi=10.1021/acs.jproteome.0c00373. (IF=5.37)

6. Ning Sheng#, Hao Zheng#, Min Li, Menglin Li, Zhe Wang, Ying Peng, Haibo Yu*, Jinlan Zhang*. 4,5 caffeoylquinic acid and scutellarin, identified by integrated metabolomics and proteomics approach as the active ingredients of Dengzhan Shengmai, act against chronic cerebral hypoperfusion by regulating glutamatergic and GABAergic synapses. Pharmacological Research, 2020, 152C, 104636. (IF=7.658)

7. Miao Lin# , Xiong Chen# , Zhe Wang , Dongmei Wang*, Jinlan Zhang*, Global profiling and identification of bile acids by multi-dimensional data mining to reveal a way of eliminating abnormal bile acids. Analytica Chimica Acta, 10.1016/j.aca.2020.07.067. (IF=6.558)

8. Miao Lin #, Zhe Wang , Dongmei Wang, Xiong Chen, Jinlan Zhang*, A mathematical model-assisted UHPLC-MS/MS method for global profiling and quantification of cholesteryl esters in hyperlipidemic golden hamster.Analytical chemistry, 2019, 91, 4504–4512.(IF=6.785)

9. Hu T#, Jia ZX, Zhang JL.*, Strategy for Comprehensive Pro?ling and Identication of Acidic Glycosphingolipids Using Ultra-High-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry. Analytical chemistry, 2017, 89, 7808?7816.(IF=6.042)

10. Tie C#, Hu T#, Jia ZX, Zhang JL.*, Derivatization Strategy for the Comprehensive Characterization of Endogenous Fatty Aldehydes Using HPLC-Multiple Reaction Monitoring.  Analytical chemistry, 2016, 88,7762-7768.(IF=6.320)